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(−) -Voacangarine

CAT: 0931-TN7544-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TN7544-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
545-84-6
Target
Others, Antifungal
Related Pathways
Others, Microbiology/Virology
Bioactivity
(–) -Voacangarine, an indole alkaloid isolated from V. africana, exhibits cytotoxicity towards various cell lines including HepG2, A375, MDA-MB-231, SH-SY5Y, and CT26 with IC50 values of 20 μg/ml. Additionally, it demonstrates cytostatic effects on wild-type S. cerevisiae and is cytotoxic to Δrad3-e5 and Δrad6-1 mutant strains of S. cerevisiae, which have defects in DNA strand break repair and the mutagenic repair pathway, respectively.
Smiles
C(OC)(=O)[C@]12C3=C(C=4C(N3)=CC=C(OC)C4)CC[N@@]5[C@]1([C@@]([C@H](C)O)(C[C@](C2)(C5)[H])[H])[H]
Molecular Formula
C22H28N2O4
Molecular Weight
384.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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