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4-methoxylonchocarpin

CAT: 0931-TN7235-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-TN7235-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
51589-67-4
Target
NF-κB, TLR, Interleukin, TNF
Related Pathways
Immunology/Inflammation, Apoptosis, NF-κB
Purity
0.9867
Bioactivity
4-methoxylonchocarpin was isolated from the roots of Abrus precatorius as a potent anti-inflammatory compound. 4-methoxylonchocarpin inhibited NF-κB-activated TNF expression by inhibiting the binding of LPS to TLR4 in macrophages and suppressed TNBS-induced colitis in mice.
Smiles
OC1=C2C(OC(C)(C)C=C2)=CC=C1C(/C=C/C3=CC=C(OC)C=C3)=O
Molecular Formula
C21H20O4
Molecular Weight
336.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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