Ethyl salvianolate A

• Target:

  HIV Protease|||Reverse Transcriptase

• Related Pathways:

  Proteases/Proteasome|||Microbiology/Virology

• Bioactivity:

  Ethyl salvianolate A (Ethyl salvionolate A) is an anti-HIV-1 compound extracted from the roots of Salvia yunnanensis. It inhibits the P24 antigen in HIV-1 infected MT-4 cell cultures with an EC50 of 1.44 ?g/mL. Additionally, it suppresses HIV-1 enzymes with IC50s of 56.38 ?M (reverse transcriptase), 12.03 ?M (protease), and 14.54 ?M (integrase) .

• Smiles:

  C(=C/C1=CC(O)=C(O)C=C1)\C2=C(/C=C/C(O[C@H](CC3=CC(O)=C(O)C=C3)C(OCC)=O)=O)C=CC(O)=C2O

• Molecular Formula:

  C28H26O10

• Molecular Weight:

  522.5

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1015171-68-2