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Merulidial

CAT: 0931-TN11385-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TN11385-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
68053-32-7
Target
Antifungal, DNA/RNA Synthesis, Antibiotic, Antibacterial
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Microbiology/Virology
Bioactivity
Merulidial (Compound 1) is an antibiotic and cytotoxic agent characterized by a sesquiterpene dialdehyde structure. It effectively inhibits the spore germination and mycelial growth of the wood-decaying basidiomycete Heterobasidion annosum (H. annosum) and the saprophytic fungus Cladosporium cucumerinum (C. cucumerinum) . Additionally, Merulidial suppresses DNA synthesis in various bacteria, algae, and ECA cells. It exhibits strong anticancer activity, with IC50 values of 20 μg/mL for ECA cells and 10 μg/mL for L1210 cells.
Smiles
C(=O)[C@@]12[C@@](C)(C1)[C@@H](O)[C@]3(C(=C2C=O)CC(C)(C)C3)[H]
Molecular Formula
C15H20O3
Molecular Weight
248.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
GTR19266175-01Merulidial

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