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Complement C8 gamma Protein, Human, Recombinant (His)

CAT: 0931-TMPJ-00585-01Size: 5 µgDry Ice: NoHazardous: No
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CAT#:0931-TMPJ-00585-01Size:5 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Bioactivity
Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G. C8G is a secreted protein and comsists a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 alpha and C8 beta play an important role in complement-mediated bacterial killing together.C8 is involved in the formation of Membrane Attack Complex on bacterial cell membranes. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. Patients lacking C8 are susceptible to certain bacterial infections.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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