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Pridinol-d5

CAT: 0804-HY-B1343AS-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1343AS-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pridinol-d5 is deuterium labeled Pridinol. Pridinol is an orally active, blood-brain permeable, muscarinic acetylcholine receptor (mAChR) -directed muscle relaxant. Pridinol reduces the conduction of impulses to spinal motor neurons and exerts muscle relaxant activity. Pridinol inhibits skeletal muscle contractures in diseases of both central and peripheral origin and can be used in research in the field of musculoskeletal diseases[2][3].
UNSPSC
12352005
Target
Cholinesterase (ChE) ; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Neuronal Signaling; Others
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
OC(C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])(CCN2CCCCC2)C3=CC=CC=C3
Molecular Formula
C20H20D5NO
Molecular Weight
300.45
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Richter M, et al. Pharmacokinetics of oral pridinol: Results of a randomized, crossover bioequivalence trial in healthy subjects. Int J Clin Pharmacol Ther. 2021 Jun;59 (6) :471-477.|[3]Lauricella L, et al. Effectiveness rehabilitative therapy and Pridinol Mesylate in low back pain. Front Med (Lausanne) . 2025 Jan 22;11:1470996.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported