IBI-325

CAT: 0931-T9901A-1902-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T9901A-1902-01Size:1 mg
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Target
TNF|||IFNAR|||Interleukin|||CD73
Related Pathways
Apoptosis|||Immunology/Inflammation
Bioactivity
IBI-325 is a humanized monoclonal antibody inhibitor targeting CD73. It completely inhibits CD73 enzymatic activity without causing a hook effect. IBI-325 can reverse adenosine monophosphate-mediated immunosuppression and significantly inhibits T cell proliferation and the release of cytokines (IL-2, IFN-?, and TNF-?) . In both hPBMC-reconstituted mouse models and hCD73 knock-in mouse models, IBI-325 demonstrates potent antitumor activity. This compound is applicable for cancer immunotherapy research.
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Popular Products