MAb604.107

• Target:

  Gamma-secretase

• Related Pathways:

  Proteases/Proteasome|||Stem Cells|||Neuroscience

• Bioactivity:

  MAb604.107 is a human monoclonal antibody targeting NOTCH1. It inhibits the proliferation of primary T-ALL cells and reduces CD34/CD44 expression. MAb604.107 demonstrates antitumor activity in four tumor xenograft mouse models: MDA-MB-231, HCC-1806, BT-474, and HCT-116. It can be utilized in research on T acute lymphoblastic leukemia (T-ALL) .

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C