XOMA-213

• Target :

  Estrogen Receptor/ERR

• Related Pathways :

  Endocrinology/Hormones

• Bioactivity :

  XOMA-213 (LFA-102; X213) is a human monoclonal antibody (mAb) that specifically targets the PRLR/Prolactin Receptor. It inhibits hPRL-dependent growth of BaF3/hPRLR cells with an EC50 of 0.5 ?g/mL. In models such as the Nb2-11-luc xenograft mouse and the DMBA-induced rat breast cancer model, XOMA-213 effectively suppresses PRLR signaling and tumor growth. This compound is applicable in research focused on breast cancer, hyperprolactinemia, and prostate cancer.

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C