MP-RM-1

CAT: 0931-T9901A-1055-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T9901A-1055-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

PI3K, EGFR, Akt

Related Pathways

PI3K/Akt/mTOR signaling, JAK/STAT signaling, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling, Angiogenesis

Bioactivity

MP-RM-1 is a selective murine monoclonal antibody inhibitor that targets the human epidermal growth factor receptor 3 (ErbB-3) . It blocks ErbB-3 activation induced by neuregulin 1 (NRG-1β), facilitates ErbB-3 internalization and degradation, and inhibits downstream signaling pathways like PI3K-Akt. MP-RM-1 shows potential for research on ErbB-3-overexpressing solid tumors such as breast cancer, melanoma, and prostate cancer.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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HY-P991243	MP-RM-1
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MP-RM-1

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