Indusatumab vedotin

• Target:

  Others|||Antibody-Drug Conjugates (ADCs) |||Apoptosis|||Guanylate cyclase

• Related Pathways:

  GPCR/G Protein|||Apoptosis|||Antibody-drug Conjugate/ADC Related|||Others

• Bioactivity:

  Indusatumab vedotin (MLN-0264; AKT-264) is an antibody-drug conjugate (ADC) that combines a human anti-guanylate cyclase C (GCC) antibody with the microtubule-disruptor monomethyl auristatin E, demonstrating anti-proliferative effects on pancreatic cancer cell lines by arresting the cell cycle at the G2/M phase and inducing apoptosis [1].

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1514889-12-3