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Disitamab vedotin

CAT: 0931-T39595-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T39595-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2136633-23-1
Target
EGFR, Antibody-Drug Conjugates (ADCs)
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, Antibody-drug Conjugate/ADC Related, JAK/STAT signaling
Purity
0.98
Bioactivity
Disitamab vedotin (RC-48) is a newly developed antibody-active molecule conjugate (ADC) targeting human epidermal growth factor receptor 2 (HER2), consisting of hertuzumab coupled to monomethyl auristatin E (MMAE) via a cleavable linker. Disitamab vedotin showed anti-tumor and anti-proliferative activities in gastric cancer cells with different HER-2 expression levels and inhibited the expression of HER-2 protein in gastric cancer cells.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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