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ONC213

CAT: 0931-T89999-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T89999-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1977540-13-8
Target
Apoptosis
Related Pathways
Apoptosis
Bioactivity
ONC213, an αKGDH inhibitor, functions by hindering αKGDH activity, thus suppressing mitochondrial respiration and elevating α-ketoglutarate levels, ultimately inducing apoptosis (Apoptosis) in AML cells. It is utilized in the study of acute myeloid leukemia.
Smiles
O=C1C2=C(N3C(=NCC3)N1CC4=CC=C(F)C(F)=C4)CCN(CC=5C=CC=CC5)C2
Molecular Formula
C23H22F2N4O
Molecular Weight
408.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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