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4-FPBUA

CAT: 0931-T89888-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T89888-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2089636-93-9
Target
Autophagy, mTOR
Related Pathways
PI3K/Akt/mTOR signaling, Autophagy
Bioactivity
4-FPBUA, a semi-synthetic analog of lichen acid, enhances the functionality of cell-based blood-brain barriers (BBB) and increases the transport of β-amyloid (Aβ) in monolayer cells. Additionally, it acts as an inhibitor of mTOR, enhancing cellular autophagy (Autophagy) which can reverse BBB disruption in vivo, making it relevant for research in Alzheimer's disease.
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C[C@]12C=3C(OC1=CC(O)=C(C(C)=O)C2=O)=C(C(/C=C/C4=CC=C(C=C4)C5=CC=C(F)C=C5)=O)C(O)=C(C)C3O
Molecular Formula
C31H23FO7
Molecular Weight
526.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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