BRD-810

• Target :

  Caspase|||Bcl-2 Family|||Apoptosis

• Related Pathways :

  Proteases/Proteasome|||Apoptosis

• Purity :

  0.9788

• Bioactivity :

  BRD-810 is a highly selective MCL1 inhibitor (Kd=0.3 nM) capable of inducing tumour cell apoptosis, suitable for studying haematological malignancies and solid tumours. BRD-810 binds the BH3 groove of MCL1, activates Caspase, and disrupts the MCL1-BAK complex in cancer cells (IC50=1.2 nM) .

• Smiles :

  ClC1=C2C3=C(C(CCCOC=4C5=C(C=CC4)C=C(F)C=C5)=C(C(O)=O)N3CCCCO[C@H](CCN6CCOCC6)C=7C2=C(CC)N(C)N7)C=C1

• Molecular Formula :

  C39H44ClFN4O5

• Molecular Weight :

  703.24

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2329719-65-3