BRD-810

CAT: 0931-MF-0095522-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0095522-01Size:1 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2329719-65-3
Target
Caspase|||Bcl-2 Family|||Apoptosis
Related Pathways
Proteases/Proteasome|||Apoptosis
Purity
0.9788
Bioactivity
BRD-810 is a highly selective MCL1 inhibitor (Kd=0.3 nM) capable of inducing tumour cell apoptosis, suitable for studying haematological malignancies and solid tumours. BRD-810 binds the BH3 groove of MCL1, activates Caspase, and disrupts the MCL1-BAK complex in cancer cells (IC50=1.2 nM) .
Smiles
ClC1=C2C3=C(C(CCCOC=4C5=C(C=CC4)C=C(F)C=C5)=C(C(O)=O)N3CCCCO[C@H](CCN6CCOCC6)C=7C2=C(CC)N(C)N7)C=C1
Molecular Formula
C39H44ClFN4O5
Molecular Weight
703.24
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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