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TY-011

CAT: 0931-T89833-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T89833-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1389439-77-3
Target
Aurora Kinase
Related Pathways
Cell Cycle/Checkpoint|||Chromatin/Epigenetic
Bioactivity
TY-011 is an inhibitor of Aurora A/B kinases. This compound induces DNA damage and cell apoptosis (Apoptosis) in human gastric cancer cells by promoting abnormal microtubule-kinetochore attachments, effectively suppressing cancer cell proliferation. The IC50 values for TY-011 in human gastric cancer cell lines range from 0.11-4.49 ?M. It is utilized in research focused on gastric cancer.
Smiles
ClC=1C=CC=CC1C2=NC=3C(=NNC3C)NC=4C=C(N=CC24)CC
Molecular Formula
C18H16ClN5
Molecular Weight
337.81
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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