TY-011

• Target :

  Aurora Kinase

• Related Pathways :

  Cell Cycle/Checkpoint|||Chromatin/Epigenetic

• Bioactivity :

  TY-011 is an inhibitor of Aurora A/B kinases. This compound induces DNA damage and cell apoptosis (Apoptosis) in human gastric cancer cells by promoting abnormal microtubule-kinetochore attachments, effectively suppressing cancer cell proliferation. The IC50 values for TY-011 in human gastric cancer cell lines range from 0.11-4.49 ?M. It is utilized in research focused on gastric cancer.

• Smiles :

  ClC=1C=CC=CC1C2=NC=3C(=NNC3C)NC=4C=C(N=CC24)CC

• Molecular Formula :

  C18H16ClN5

• Molecular Weight :

  337.81

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1389439-77-3