N3-TFBA-O2Oc

CAT: 0931-T89751-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T89751-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1993119-45-1

Target

ADC Linker

Related Pathways

Antibody-drug Conjugate/ADC Related

Bioactivity

N3-TFBA-O2Oc is a photochemical probe comprising azide and aryl groups. This type of azidoaryl compound serves as a classical precursor to nitro compounds and has been utilized by Fleet et al as a versatile photophore for probing biological receptors. Specifically, N3-TFBA-O2Oc functions as a photo-crosslinker (λmax=258 nm) in studies involving estrogen receptors and for direct surface coating of carbon and organic polymers. Additionally, as a click chemistry reagent, N3-TFBA-O2Oc contains an azide group that reacts with molecules featuring an alkyne group through a copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) . It can also engage in strain-promoted azide-alkyne cycloaddition reactions (SPAAC) with molecules that possess DBCO or BCN groups.

Smiles

[N-]=[N+]=NC1=C(F)C(F)=C(C(=O)NCCOCCOCC(=O)O)C(F)=C1F

Molecular Formula

C13H12F4N4O5

Molecular Weight

380.25

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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GTR19237601-01	N3-TFBA-O2Oc
GTR19237684-01	N3-O2Oc-O2Oc-OH
sc-293923A	Boc-O2Oc-O2Oc-OH
sc-293924A	Boc-O2Oc-OH*DCHA
sc-296850A	Z-O2Oc-OH*DCHA
sc-284958A	Aloc-O2Oc-OH DCHA
abx085048-01	N3-PEG-N3
MD006006-2	N3-PEG2-N3
MD006006-6	N3-PEG6-N3
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N3-TFBA-O2Oc

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