MPro N3

• Target:

  SARS-CoV|||Others|||Virus Protease

• Related Pathways:

  Microbiology/Virology|||Others

• Bioactivity:

  Coronavirus main protease (Mpro) inhibitor (respective IC50 values are 2.7, 4 and 8.8 ?M for MHV-A29, HCoV-229E and FOPV replication in vitro) . Inhibits viral cell infection in an MHV plaque reduction assay. Also inhibits SARS-CoV-2 viral cell entry in a plaque reduction assay (IC50 = 16.8 ?M) .

• Smiles:

  [C@@H](C[C@H]1C(=O)NCC1)(NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)C=2C=C(C)ON2)C)=O)C(C)C)=O)CC(C)C)=O)/C=C/C(OCC3=CC=CC=C3)=O

• Molecular Formula:

  C35H48N6O8

• Molecular Weight:

  680.79

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  884650-98-0