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Bimokalner

CAT: 0931-T89562-02Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-T89562-02Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2243284-19-5
Bioactivity
Bimokalner (Bimokalnerum) is an activator of the voltage-gated potassium channel (Kv7.4) .
Smiles
C(NCC1=CC(S(F)(F)(F)(F)F)=CC=C1)(=O)[C@@H]2[C@@]3(C[C@](C2)(CC3)[H])[H]
Molecular Formula
C15H18F5NOS
Molecular Weight
355.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Bimokalner

Bimokalner is a small molecule drug. The usage of the INN stem '-kalner' in the name indicates that Bimokalner is a opener of calcium-activated (maxi-K) K+-channel. Bimokalner is under investigation in clinical trial NCT06521190 (ACOU085 for Hearing Loss Prevention in Testicular Cancer Patients Receiving Cisplatin). Bimokalner has a monoisotopic molecular weight of 355.1 Da.

CAS Number2243284-19-5
PubChem CID135309173
IUPAC Name(1S,2S,4R)-N-[[3-(pentafluoro-lambda6-sulfanyl)phenyl]methyl]bicyclo[2.2.1]heptane-2-carboxamide
Molecular FormulaC15H18F5NOS
Molecular Weight355.4
XLogP6.3
Topological Polar Surface Area30.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Heavy Atom Count23
Formal Charge0
Complexity493
SMILES
C1C[C@H]2C[C@@H]1C[C@@H]2C(=O)NCC3=CC(=CC=C3)S(F)(F)(F)(F)F
InChI
InChI=1S/C15H18F5NOS/c16-23(17,18,19,20)13-3-1-2-11(7-13)9-21-15(22)14-8-10-4-5-12(14)6-10/h1-3,7,10,12,14H,4-6,8-9H2,(H,21,22)/t10-,12+,14+/m1/s1
InChIKey
KTTBVFVRXDRSSP-OSMZGAPFSA-N
Chemical Structure
2D Structure
2D structure of Bimokalner
CAS: 2243284-19-5
CID: 135309173
Formula: C15H18F5NOS
MW: 355.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight355.4
XLogP36.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Exact Mass355.10292618
Monoisotopic Mass355.10292618
Topological Polar Surface Area30.1 Ų
Heavy Atom Count23
Formal Charge0
Complexity493
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
HY-159506Bimokalner

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