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WX8

CAT: 0931-T89407-02Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-T89407-02Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
232935-92-1
Bioactivity
WX8 (Ro 91-4714) is an ATP-competitive inhibitor of PIKFYVE, displaying Kd values of 0.9 nM for PIKFYVE and 340 nM for PIP4K2C. This compound inhibits lysosomal fission without affecting homotypic lysosome fusion. WX8 (Ro 91-4714) is applicable in research on autophagy-dependent cancers.
Smiles
N(=CC1=CNC=2C=CC=CC12)NC=3N=C(N=C(N3)N4CCOCC4)NC=5C=CC=CC5
Molecular Formula
C22H22N8O
Molecular Weight
414.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

1H-indole-3-carbaldehyde [4-anilino-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone
CAS Number232935-92-1
PubChem CID135510930
IUPAC Name2-N-[(E)-1H-indol-3-ylmethylideneamino]-6-morpholin-4-yl-4-N-phenyl-1,3,5-triazine-2,4-diamine
Molecular FormulaC22H22N8O
Molecular Weight414.5
XLogP4
Topological Polar Surface Area103
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count8
Rotatable Bond Count6
Heavy Atom Count31
Formal Charge0
Complexity580
SMILES
C1COCCN1C2=NC(=NC(=N2)N/N=C/C3=CNC4=CC=CC=C43)NC5=CC=CC=C5
InChI
InChI=1S/C22H22N8O/c1-2-6-17(7-3-1)25-20-26-21(28-22(27-20)30-10-12-31-13-11-30)29-24-15-16-14-23-19-9-5-4-8-18(16)19/h1-9,14-15,23H,10-13H2,(H2,25,26,27,28,29)/b24-15+
InChIKey
NJIKLALXAPYTCW-BUVRLJJBSA-N
Chemical Structure
2D Structure
2D structure of 1H-indole-3-carbaldehyde [4-anilino-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone
CAS: 232935-92-1
CID: 135510930
Formula: C22H22N8O
MW: 414.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight414.5
XLogP34
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count8
Rotatable Bond Count6
Exact Mass414.19165736
Monoisotopic Mass414.19165736
Topological Polar Surface Area103 Ų
Heavy Atom Count31
Formal Charge0
Complexity580
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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