Products for Research Use Only

HSP70-IN-6

CAT: 0931-T89363-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T89363-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
HSP, Apoptosis, Bcl-2 Family
Related Pathways
Apoptosis, Cytoskeletal Signaling, Metabolism
Bioactivity
HSP70-IN-6 (Compound JL-15) acts as an inhibitor of the Hsp70-Bim protein-protein interactions (PPI) with an IC50 value of 70 nM. It induces apoptosis in chronic myeloid leukemia (CML) cells with EC50 values of 0.43 μM (BV173), 0.88 μM (K562), and 0.19 μM (K562-R3) .
Shipping Conditions
Ice Packs
Storage Temperature
-20°C