Products for Research Use Only
RegisterLogin

DdhCTP

CAT: 0931-T89215-03Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T89215-03Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2279171-34-3
Bioactivity
DdhCTP, a nucleoside analog, inhibits DNA synthesis by specifically targeting the activity of DNA polymerases. It demonstrates inhibition constants (Ki) of 1.32 and 0.034 μM for DNA polymerase β and DNA polymerase γ, respectively.
Smiles
O[C@H]1[C@@H](OC(COP(OP(OP(=O)(O)O)(=O)O)(=O)O)=C1)N2C(=O)N=C(N)C=C2
Molecular Formula
C9H14N3O13P3
Molecular Weight
465.14
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

3'-deoxy-3',4'-didehydro-CTP

3'-deoxy-3',4'-didehydro-CTP is an organic triphosphate resulting from the formal condensation of the 5'-hydroxy group of 3'-deoxy-3',4'-didehydro-cytidine with triphosphoric acid. It is a chain terminator for RNA-dependent RNA polymerases. It has a role as an EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor, an antiviral agent and an antimetabolite. It is a pyrimidone and an organic triphosphate. It is functionally related to a 3'-deoxy-3',4'-didehydro-cytidine. It is a conjugate acid of a 3'-deoxy-3',4'-didehydro-CTP(4-).

CAS Number2279171-34-3
PubChem CID137520688
IUPAC Name[[(2R,3R)-2-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxy-2,3-dihydrofuran-5-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Molecular FormulaC9H14N3O13P3
Molecular Weight465.14
XLogP-5.7
Topological Polar Surface Area248
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count13
Rotatable Bond Count8
Heavy Atom Count28
Formal Charge0
Complexity878
SMILES
C1=CN(C(=O)N=C1N)[C@H]2[C@@H](C=C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O
InChI
InChI=1S/C9H14N3O13P3/c10-7-1-2-12(9(14)11-7)8-6(13)3-5(23-8)4-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-3,6,8,13H,4H2,(H,18,19)(H,20,21)(H2,10,11,14)(H2,15,16,17)/t6-,8-/m1/s1
InChIKey
DGUQXKKDZHTKIE-HTRCEHHLSA-N
Chemical Structure
2D Structure
2D structure of 3'-deoxy-3',4'-didehydro-CTP
CAS: 2279171-34-3
CID: 137520688
Formula: C9H14N3O13P3
MW: 465.14
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight465.14
XLogP3-5.7
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count13
Rotatable Bond Count8
Exact Mass464.97394850
Monoisotopic Mass464.97394850
Topological Polar Surface Area248 Ų
Heavy Atom Count28
Formal Charge0
Complexity878
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
B8293-25ddhCTP
dNTP040-10DdhCTP 100mM Sodium Solution

Popular Products