JJC8-089

• Bioactivity:

  JJC8-089, a dopamine transporter (DAT) inhibitor, might enhance motivation-related dysfunctions by increasing effortful behavior in goal-oriented activities. This compound significantly counteracted the low-effort effects induced in rats by the VMAT-2 inhibitor Tetrabenazine, and elevated the selection of high-effort fixed ratio 5 lever presses associated with food intake.

• Smiles:

  FC1=CC=C(C=C1)C(SCCN2CCN(CC2)CC(O)C)C3=CC=C(F)C=C3

• Molecular Formula:

  C22H28F2N2OS

• Molecular Weight:

  406.53

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1627576-64-0