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HDAC6-IN-48

CAT: 0931-T89065-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T89065-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Apoptosis, HDAC
Related Pathways
Apoptosis, DNA Damage/DNA Repair, Chromatin/Epigenetic
Bioactivity
HDAC6-IN-48 (compound 5i) is a potent and selective inhibitor of HDAC6, exhibiting IC50 values of 5.16, 396.72, and 638.08 nM against HDAC6, HDAC3, and HDAC1, respectively. This compound induces cell apoptosis and arrests the cell cycle at the G0/G1 phase. Furthermore, HDAC6-IN-48 enhances the expression of acetylated α-tubulin.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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