Products for Research Use Only
RegisterLogin

RPS6-IN-1

CAT: 0931-T88975-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T88975-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Bcl-2 Family, Caspase, PARP, Apoptosis, Autophagy, MDM-2/p53
Related Pathways
DNA Damage/DNA Repair, Proteases/Proteasome, Autophagy, Apoptosis, Chromatin/Epigenetic
Bioactivity
RPS6-IN-1 (Compound 22o) inhibits cell migration and induces apoptosis (increasing the expression of Bax, p53, cleaved-caspase 3, and cleaved-PARP) . It reduces mitochondrial membrane potential and activates autophagy (Autophagy) through the PI3K-Akt-mTOR signaling pathway, damaging mitochondria and lysosomes within the cell and causing endoplasmic reticulum stress. RPS6-IN-1 also inhibits the phosphorylation of RPS6. Notably, RPS6-IN-1 is a low systemic toxicity anticancer agent.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
TMAB-12368-01Anti-RPS6 Polyclonal Antibody
TMAB-12367-01Anti-RPS6 (N-term) Antibody (1F700)
TMAB-11246-01Anti-Phospho-RPS6 (Ser235+Ser236) Polyclonal Antibody
TMAB-11247-01Anti-Phospho-RPS6 (Ser235+Ser236) Antibody (5J79)
TMAB-11245-01Anti-Phospho-RPS6 (Ser235/Ser236) Antibody (1R109)
TMAB-11248-01Anti-Phospho-RPS6 (Ser240+Ser244) Polyclonal Antibody
TMAB-11249-01Anti-Phospho-RPS6 (Ser240+Ser244) Antibody (1M749)
T5790-011,1,1,1-Kestohexaose
T83125-01AMPK-α1β1γ1 activator 1
T404761,1,1-Tribromoacetone

Alternative Products

CatalogName
HY-161874RPS6-IN-1
CSB-CL020463HU1RPS6
GTR17959138RPS6 Antibody
502391RPS6, NT
AF6637-BPRPS6 Peptide
P9083POTB7-RPS6

Popular Products