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JMV6944

CAT: 0931-T88936-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T88936-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2871774-93-3
Bioactivity
JMV6944 is a PXR agonist that competitively inhibits the binding of ligands to the ligand-binding domain (LBD) of human PXR, with an IC50 value of 680 nM. Additionally, JMV6944 induces the expression of CYP3A4 mRNA in cultures of freshly isolated primary human hepatocytes.
Smiles
O=S(=O)(NC=1C=CC2=C(N=C(N2CC=3C=CC=CC3)CCCCCCCN)C1)C=4C(=CC(=CC4C)C)C
Molecular Formula
C30H38N4O2S
Molecular Weight
518.71
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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