Products for Research Use Only

JMV6944

CAT: 0013-GTR19238413-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19238413-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JMV6944 is a potent small molecule PXR agonist with an IC50 of 680 nM, competitively inhibiting ligand binding to the PXR LBD. It induces CYP3A4 mRNA expression in primary human hepatocytes, making it a valuable tool for studying drug metabolism, receptor antagonism, and enzyme induction in vitro.
CAS Number
2871774-93-3
Smiles
O=S (=O) (NC=1C=CC2=C (N=C (N2CC=3C=CC=CC3) CCCCCCCN) C1) C=4C (=CC (=CC4C) C) C
Molecular Formula
C30H38N4O2S
Molecular Weight
518.71
Storage Conditions
-20°C
Notes
For research use only.

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CatalogName
T88936-01JMV6944