Products for Research Use Only
RegisterLogin

BA6b9

CAT: 0931-T88799-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T88799-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
609335-29-7
Target
Potassium Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
BA6b9 is an allosteric inhibitor targeting the SK4 channel via the CaM-PIP2 binding domain. It interacts with two critical residues, Arg191 and His192, located in the S4-S5 linker to inhibit the SK4 channel, with an IC50 of 8.6 μM (WT SK4) . BA6b9 significantly prolongs the effective refractory period (ERP) of the atria and atrioventricular node in isolated rat hearts, reducing the induction of atrial fibrillation (AF), highlighting its potential for arrhythmia research.
Smiles
O=C1OC=2C=CC=CC2N1CCCCCCC
Molecular Formula
C14H19NO2
Molecular Weight
233.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-163735BA6b9

Popular Products