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VU0448088

CAT: 0931-T88709-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T88709-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1417616-42-2
Target
AChR
Related Pathways
Neuroscience
Bioactivity
VU0448088 (ML253) is a potent positive allosteric modulator of the tricyclic muscarinic acetylcholine receptor subtype 4 (M4) and can cross the blood-brain barrier. It exhibits EC50 values of 56 nM and 176 nM in humans and rats, respectively. The compound VU0448088 holds potential for use in psychiatric research.
Smiles
O=C(NCC=1C=CN=CC1)C=2SC3=NC(=C(Cl)C(=C3C2N)C)C
Molecular Formula
C16H15ClN4OS
Molecular Weight
346.83
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
GTR19236328-01VU0448088

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