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YY173

CAT: 0931-T88647-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T88647-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
330550-51-1
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Bioactivity
YY173 is a dual inhibitor of CDK4 and CDK6, with IC50 values of 7.7 and 88 nM, respectively. It inhibits the proliferation of Jurkat cells with an IC50 of 1.46 μM. Additionally, YY173 can be utilized in the synthesis of PROTAC CDK4/6 degrader 1.
Smiles
O=C1C=NC=2C=NC(=NC2N1C3CCCC3)NC4=CC=C(C=C4)N5CCNCC5
Molecular Formula
C21H25N7O
Molecular Weight
391.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
GTR19236392-01YY173

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