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REM127

CAT: 0931-T88556-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T88556-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1417823-67-6
Target
Calcium Channel, Beta Amyloid, Others
Related Pathways
Neuroscience, Metabolism, Membrane transporter/Ion channel, Others
Bioactivity
REM127 is a small molecular compound that modulates cellular calcium homeostasis and provides neuroprotection. It efficiently restores the imbalance of calcium homeostasis in cell models caused by the pathological accumulation of tau protein. Furthermore, REM127 can effectively cross the blood-brain barrier and offers therapeutic benefits in animal models of Alzheimer's disease, particularly in ameliorating synaptic and cognitive deficits and slowing the progression of amyloid-beta and tau pathologies. This compound is utilized in the research of neurodegenerative diseases.
Smiles
ClC=1C=CC(=CC1)C2=NSC(=N2)N3CCN(CCC=4C=CC=CC4Cl)CC3
Molecular Formula
C20H20Cl2N4S
Molecular Weight
419.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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CatalogName
E5930-01REM127

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