BMS-737

• Target :

  Cytochromes P450

• Related Pathways :

  Metabolism

• Bioactivity :

  BMS-737 (compound 33), a non-steroidal, reversible small molecule inhibitor, demonstrates 11-fold selectivity for CYP17 lyase over CYP17 hydroxylase. This compound is engineered to target castration-resistant prostate cancer (CRPC) and effectively lowers testosterone levels, while maintaining stable orrodermal hormone and glucocorticoid levels.

• Smiles :

  FC1=CC=C(C=C1)N2N=CC=3C2=NC=CC3C=4C=NC=NC4N

• Molecular Formula :

  C16H11FN6

• Molecular Weight :

  306.3

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1356053-63-8