DNMT1-IN-3

• Target :

  DNA Methyltransferase

• Related Pathways :

  Chromatin/Epigenetic

• Bioactivity :

  DNMT1-IN-3 (compound 7t-S), a DNMT1 inhibitor, exhibits an IC50 of 0.777 ?M. It induces cell apoptosis and leads to G0/G1 phase arrest.

• Smiles :

  C([C@@H](C(O)=O)N1C(=O)C=2C(C1=O)=CC=CC2)N3C=4C(C=5C3=CC=C(Cl)C5)=CC(Cl)=CC4Cl

• Molecular Formula :

  C23H13Cl3N2O4

• Molecular Weight :

  487.72

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  3025012-68-1