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Fosmidomycin

CAT: 0931-T88195-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T88195-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
66508-53-0
Target
Antibiotic, Parasite
Related Pathways
Microbiology/Virology
Bioactivity
Fosmidomycin is an orally administered antibiotic that demonstrates antimalarial properties by inhibiting 1-deoxy-D-xylulose 5-phosphate (DOXP) reductoisomerase. It effectively inhibits the P. falciparum strains 3D7, HB3, Dd2, and A2, with IC 50 values of 150, 71, 170, and 150 ng/mL, respectively. Fosmidomycin works synergistically with Clindamycin and alleviates malaria in a mouse model.
Smiles
O=CN(O)CCCP(=O)(O)O
Molecular Formula
C4H10NO5P
Molecular Weight
183.1
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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