TF-S14

• CAS Number :

  2425563-60-4

• Target :

  ROR

• Related Pathways :

  Metabolism

• Bioactivity :

  TF-S14 is an inverse agonist of ROR?t. It functions by binding to ROR?t and inhibiting its activity, leading to a reduction in Th17 cell-associated cytokine production, including IL-17A, IL-21, and IL-22. TF-S14 is applicable in research related to autoimmune diseases and allogeneic transplant rejection.

• Smiles :

  C(=O)(C=1C2=C(SC1NC(=O)C=3C=CC=NC3)CCCC2)N4[C@H](C)C[C@H](C)CC4

• Molecular Formula :

  C22H27N3O2S

• Molecular Weight :

  397.53

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C