NVS-STG2

• Bioactivity:

  NVS-STG2 is a STING agonist that promotes the oligomerization of human STING by binding to the pockets between adjacent STING dimer transmembrane domains, effectively acting as molecular glue. It triggers strong STING-mediated immune responses in cells and demonstrates antitumor activity in hSTING knock-in mice.

• Smiles:

  O=C(O)C1=CC=C(NCC2=CC=C(C=C2)C3(OCC(C)(C)CO3)C(C)(C)C)C(OC)=C1

• Molecular Formula:

  C25H33NO5

• Molecular Weight:

  427.54

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3030588-01-0