NVS-STG2

• Bioactivity :

  NVS-STG2 is a STING agonist that promotes the oligomerization of human STING by binding to the pockets between adjacent STING dimer transmembrane domains, effectively acting as molecular glue. It triggers strong STING-mediated immune responses in cells and demonstrates antitumor activity in hSTING knock-in mice.

• Smiles :

  O=C(O)C1=CC=C(NCC2=CC=C(C=C2)C3(OCC(C)(C)CO3)C(C)(C)C)C(OC)=C1

• Molecular Formula :

  C25H33NO5

• Molecular Weight :

  427.54

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  3030588-01-0