NVS-SM2

• Target:

  Others|||DNA/RNA Synthesis

• Related Pathways:

  DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Others

• Bioactivity:

  NVS-SM2 is an effective small molecule splicing enhancer of SMN2 with oral activity. NVS-SM2 showed increased exon 7 inclusion and upregulated SMN protein expression in SMA fibroblasts and SMN cells ?7 5025 mouse myoblasts.

• Smiles:

  CN(C1CC(C)(C)NC(C)(C)C1)c1ccc(nn1)-c1ccc(cc1O)-c1cn[nH]c1

• Molecular Formula:

  C23H30N6O

• Molecular Weight:

  406.52

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1562333-92-9