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NVS-SM2

CAT: 0931-T33764-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T33764-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1562333-92-9
Target
Others, DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Others
Bioactivity
NVS-SM2 is an effective small molecule splicing enhancer of SMN2 with oral activity. NVS-SM2 showed increased exon 7 inclusion and upregulated SMN protein expression in SMA fibroblasts and SMN cells Δ7 5025 mouse myoblasts.
Smiles
CN(C1CC(C)(C)NC(C)(C)C1)c1ccc(nn1)-c1ccc(cc1O)-c1cn[nH]c1
Molecular Formula
C23H30N6O
Molecular Weight
406.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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