ML-137

• Target :

  Cholinesterase (ChE)

• Related Pathways :

  Neuroscience

• Bioactivity :

  ML-137 is a positive allosteric modulator (PAM) of M1 muscarinic acetylcholine receptors (mAChRs) . ML-137 potentiates ACh-induced activation of the M1 muscarinic receptor (EC50 = 0.83 µM) .

• Smiles :

  O=C1C(=O)N(C=2C=CC=CC12)CC=3C=CC(=CC3F)C=4C=NN(C4)C

• Molecular Formula :

  C19H14FN3O2

• Molecular Weight :

  335.33

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1222834-53-8