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Methyltetrazine-PEG4-hydrazone-DBCO

CAT: 0931-T87738-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T87738-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
ADC Linker
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
Methyltetrazine-PEG4-hydrazone-DBCO, a cleavable 4-unit PEG ADC linker, serves as a click chemistry reagent in the synthesis of antibody-drug conjugates (ADCs) [1]. This compound features a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-bearing molecules. It also includes a Tetrazine group capable of engaging in an inverse electron demand Diels-Alder reaction (iEDDA) with TCO-bearing molecules.
Molecular Formula
C48H51N9O8
Molecular Weight
881.97
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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HY-136079-01Methyltetrazine-PEG4-hydrazone-DBCO
HY-W800724Methyltetrazine-PEG4-DBCO
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