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WNTinib

CAT: 0931-T87634-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T87634-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2770091-44-4
Target
Apoptosis, Wnt/beta-catenin
Related Pathways
Cytoskeletal Signaling, Apoptosis, Stem Cells
Bioactivity
WNTinib (APS-8-100-2), a multi-kinase inhibitor, selectively targets β-catenin (CTNNB1) mutated hepatocellular carcinoma (HCC) and impedes oncogenic Wnt signaling. It achieves this by inhibiting KIT/MAPK and subsequent activation of EZH2 [1].
Smiles
O(C=1C=C(C(NC)=O)N=CC1)C2=CC(F)=C(NC(NC3=CC=C(C(C(F)(F)F)(F)F)C=C3)=O)C=C2
Molecular Formula
C22H16F6N4O3
Molecular Weight
498.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
BA3152-25WNTinib

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