UCM-13369

CAT: 0931-T87591-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T87591-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2921944-77-4
Target
Apoptosis
Related Pathways
Apoptosis
Bioactivity
UCM-13369 (Compound 4b) serves as an NPM1 inhibitor, effectively downregulating the pathway linked to mutant NPM1 C+ by specifically targeting the C-terminal DNA-binding domain of NPM1 C+. It induces apoptosis in AML cell lines and primary cells, making it a valuable tool for AML research [1].
Smiles
C(CNCC1CC1)[C@@H]2C3=C(C[C@@H]([C@H]2N)C4=CC=C(OC)C=C4)NC=5C3=CC=CC5
Molecular Formula
C25H31N3O
Molecular Weight
389.53
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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