UBX-382

• Target :

  BTK

• Related Pathways :

  Angiogenesis|||Tyrosine Kinase/Adaptors

• Bioactivity :

  UBX-382 is an orally administered proteolysis-targeting chimera (PROTAC) designed to target BTK and disrupt B-cell receptor signaling. It demonstrates enhanced degradation of both wild-type and mutant BTK proteins, exhibiting anti-cancer effects in murine xenograft models using TMD-8 cells [1].

• Smiles :

  O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=C(C2)N4CCC(CN5CC=6C(CC5)=CC=C(NC=7N=C8C(=CN7)C(NC9=C(C)C=CC=C9C)=NN8C)C6)CC4

• Molecular Formula :

  C42H44N10O4

• Molecular Weight :

  752.86

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2884554-45-2