SB-1436

• Target :

  Cholinesterase (ChE)

• Related Pathways :

  Neuroscience

• Bioactivity :

  SB-1436 is a Cholinesterase (ChE) inhibitor that inhibits acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and recombinant human acetylcholinesterase (rHuAChE) with IC50 values of 0.176, 0.37, and 0.08 ?M, respectively. It inhibits AChE and BChE in a non-competitive manner with Ki values of 0.046 and 0.115 ?M, respectively. Additionally, SB-1436 significantly prevents the self-aggregation of A? and can be used for neurological disease research [1].

• Smiles :

  C(=C/C=1C=C[N+](CC2=CC=C(F)C=C2)=CC1)\C3=CC4=C(C=C(OC)C=C4)C=C3.[Cl-]

• Molecular Formula :

  C25H21ClFNO

• Molecular Weight :

  405.89

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2925298-08-2