SB-1436

CAT: 0931-T87366-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T87366-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2925298-08-2
Target
Cholinesterase (ChE)
Related Pathways
Neuroscience
Bioactivity
SB-1436 is a Cholinesterase (ChE) inhibitor that inhibits acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and recombinant human acetylcholinesterase (rHuAChE) with IC50 values of 0.176, 0.37, and 0.08 ?M, respectively. It inhibits AChE and BChE in a non-competitive manner with Ki values of 0.046 and 0.115 ?M, respectively. Additionally, SB-1436 significantly prevents the self-aggregation of A? and can be used for neurological disease research [1].
Smiles
C(=C/C=1C=C[N+](CC2=CC=C(F)C=C2)=CC1)\C3=CC4=C(C=C(OC)C=C4)C=C3.[Cl-]
Molecular Formula
C25H21ClFNO
Molecular Weight
405.89
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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