SB-1436

• Target:

  Cholinesterase (ChE)

• Related Pathways:

  Neuroscience

• Bioactivity:

  SB-1436 is a Cholinesterase (ChE) inhibitor that inhibits acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and recombinant human acetylcholinesterase (rHuAChE) with IC50 values of 0.176, 0.37, and 0.08 ?M, respectively. It inhibits AChE and BChE in a non-competitive manner with Ki values of 0.046 and 0.115 ?M, respectively. Additionally, SB-1436 significantly prevents the self-aggregation of A? and can be used for neurological disease research [1].

• Smiles:

  C (=C/C=1C=C[N+] (CC2=CC=C (F) C=C2) =CC1) \C3=CC4=C (C=C (OC) C=C4) C=C3.[Cl-]

• Molecular Formula:

  C25H21ClFNO

• Molecular Weight:

  405.89

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2925298-08-2