ORIC-533

• Target :

  CD73

• Related Pathways :

  Immunology/Inflammation

• Bioactivity :

  ORIC-533 is a selective CD73 inhibitor that is orally active and competes with AMP. It revitalizes the proliferation and activation of immunosuppressed CD8+ T cells and induces notable lysis and cell death in multiple myeloma cells within the bone marrow microenvironment [1].

• Smiles :

  O[C@H]1[C@H](N2C=3C(C=N2)=C(NC4CCCC4)N=C(Cl)N3)O[C@H](CO[C@](COCC=5NN=NN5)(P(=O)(O)O)CO)[C@H]1O

• Molecular Formula :

  C20H29ClN9O9P

• Molecular Weight :

  605.93

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2641306-62-7