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NPD10084

CAT: 0931-T87033-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T87033-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1040706-91-9
Target
PKM
Related Pathways
Metabolism
Bioactivity
NPD10084 is an inhibitor of pyruvate kinase PKM2 that blocks non-glycolytic signaling in cancer cells by disrupting PKM2's interaction with β-catenin or STAT3, thus inhibiting downstream pathways. It demonstrates antiproliferative effects against colorectal cancer cells both in vitro and in vivo [1].
Smiles
C(=O)(N1CC=2C=3C(NC2CC1)=CC=CC3)C4=CC=5C(N4)=CC=CC5OC
Molecular Formula
C21H19N3O2
Molecular Weight
345.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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