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NMD670

CAT: 0931-T87024-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T87024-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2354321-33-6
Target
Chloride channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
NMD670 is an orally active, partial inhibitor of the skeletal muscle-specific chloride channel ClC-1. It enhances muscle excitability and neuromuscular transmission, restoring muscle function and mobility. NMD670 has a favorable safety profile and improves muscle function in rats, particularly in an MG rat model [1].
Smiles
O([C@H](C(O)=O)C)C1=C(C=C(Br)C=C1)C=2C=CON2
Molecular Formula
C12H10BrNO4
Molecular Weight
312.12
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

(S)-2-(4-Bromo-2-(isoxazol-3-yl)phenoxy)propanoic acid
CAS Number2354321-33-6
PubChem CID138684045
IUPAC Name(2S)-2-[4-bromo-2-(1,2-oxazol-3-yl)phenoxy]propanoic acid
Molecular FormulaC12H10BrNO4
Molecular Weight312.12
XLogP2.7
Topological Polar Surface Area72.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Heavy Atom Count18
Formal Charge0
Complexity302
SMILES
C[C@@H](C(=O)O)OC1=C(C=C(C=C1)Br)C2=NOC=C2
InChI
InChI=1S/C12H10BrNO4/c1-7(12(15)16)18-11-3-2-8(13)6-9(11)10-4-5-17-14-10/h2-7H,1H3,(H,15,16)/t7-/m0/s1
InChIKey
XKXLEZCOELWNMB-ZETCQYMHSA-N
Chemical Structure
2D Structure
2D structure of (S)-2-(4-Bromo-2-(isoxazol-3-yl)phenoxy)propanoic acid
CAS: 2354321-33-6
CID: 138684045
Formula: C12H10BrNO4
MW: 312.12
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight312.12
XLogP32.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Exact Mass310.97932
Monoisotopic Mass310.97932
Topological Polar Surface Area72.6 Ų
Heavy Atom Count18
Formal Charge0
Complexity302
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BA6631-1NMD670

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