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MG2N001

CAT: 0931-T86893-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T86893-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2760515-88-4
Target
Src, GluR
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, Neuroscience
Bioactivity
MG2N001, a negative allosteric modulator (NAM) of the metabotropic glutamate receptor mGluR2, has an IC50 of 93 nM and binds to mGluR2 as an antagonist with a Ki of 63 nM. This compound is microparticle- and plasma-stable, and its radioisotope [11C] mG2N001 can be utilized in PET imaging. [11C] mG2N001 exhibits good brain heterogeneity and penetration, selectively accumulating in mGluR2-rich regions to produce high-contrast brain images [1].
Smiles
FC1=C(C2=C3C(=NC(C(N)=O)=C2)OC(C)(C)CC3)C=CC(OC)=C1
Molecular Formula
C18H19FN2O3
Molecular Weight
330.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-157998MG2N001

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