MDM2-IN-26

• Target:

  MDM-2/p53

• Related Pathways:

  Apoptosis

• Bioactivity:

  MDM2-IN-26 (compound A3) is an inhibitor of MDM2 that facilitates the activation of p53's tumor suppressor functions by inhibiting the MDM2-p53 interaction, with MDM2 being the primary negative regulator of p53. This compound is utilized in cancer research [1].

• Smiles:

  O=C1[C@@]2 (C3 (N[C@@H] (C (NC45CCC (C (O) =O) (CC4) CC5) =O) [C@@H]2C6=C (F) C (Cl) =CC=C6) CCC (F) (F) CC3) C=7C (N1) =CC (Cl) =CC7

• Molecular Formula:

  C32H32Cl2F3N3O4

• Molecular Weight:

  650.52

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1818393-11-1