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HDAC6-IN-33

CAT: 0931-T86554-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T86554-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2444302-23-0
Target
HDAC
Related Pathways
Chromatin/Epigenetic, DNA Damage/DNA Repair
Bioactivity
HDAC6-IN-33 (compound 6), an irreversible and selective HDAC6 inhibitor, demonstrates a potency with an IC 50 of 193 nM and lacks activity against HDAC1-4. This compound adheres to HDAC6 through a two-step slow-binding mechanism, establishing it as a tight-binding inhibitor [1].
Smiles
C(F)(F)C=1OC(=NN1)C=2C=NC(NCC3=CC=CC=C3)=NC2
Molecular Formula
C14H11F2N5O
Molecular Weight
303.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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