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GA32

CAT: 0931-T86483-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T86483-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1386811-71-7
Target
Glucocorticoid Receptor, Androgen Receptor
Related Pathways
Endocrinology/Hormones
Bioactivity
GA32 (compound 58r) is a potent androgen receptor (AR) /glucocorticoid receptor (GR) dual inhibitor with IC50 values of 0.13 μM and 0.83 μM for AR and GR, respectively. GA32 inhibits the proliferation of Enzalutamide-resistant, castration-resistant prostate cancer both in vitro and in vivo [1].
Smiles
S(=O)(=O)(N1C=2C(CCC1)=CC=CC2)C3=CC(C(NC4=CC=C(C#N)C=C4)=O)=CC=C3
Molecular Formula
C23H19N3O3S
Molecular Weight
417.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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